Top 10 Medical Billing Denial Codes Every Biller Should Know

Medical billing professionals encounter hundreds of denial codes, but a small number account for a large percentage of claim denials. Understanding these common denial codes helps providers resolve billing issues faster, improve reimbursement, and reduce future claim denials.

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5/12/20262 min read

Top 10 Medical Billing Denial Codes Every Biller Should Know

Medical billing professionals encounter hundreds of denial codes, but a small number account for a large percentage of claim denials. Understanding these common denial codes helps providers resolve billing issues faster, improve reimbursement, and reduce future claim denials.

Whether you're new to medical billing or an experienced biller, knowing these denial codes can significantly improve claim management and revenue cycle performance.

Why These Denial Codes Matter

Some denial codes appear far more frequently than others because they involve common billing mistakes such as missing information, eligibility issues, duplicate claims, and patient responsibility.

Learning these denial codes allows billing staff to identify problems quickly and take the appropriate corrective action.

1. CO-16 – Missing or Incomplete Information

One of the most common denial codes in medical billing.

This denial indicates the insurance company needs additional information before the claim can be processed.

Common causes include:

  • Missing documentation

  • Incomplete claim fields

  • Invalid patient information

Learn more: CO-16 Denial Code

2. CO-18 – Duplicate Claim or Service

CO-18 indicates the payer believes the service has already been submitted or processed.

Before resubmitting a claim, providers should verify the original claim status.

Learn more: CO-18 Denial Code

3. CO-22 – Coordination of Benefits Required

CO-22 occurs when the insurance company requires additional coordination of benefits (COB) information before processing payment.

Providers should verify primary and secondary insurance coverage before resubmitting the claim.

Learn more: CO-22 Denial Code

4. PR-1 – Deductible Amount

PR-1 indicates the patient's deductible applies to the billed service.

This amount is generally the patient's financial responsibility.

Learn more: PR-1 Denial Code

5. PR-2 – Coinsurance Amount

PR-2 identifies the portion of the claim that the patient must pay as coinsurance according to their insurance plan.

Learn more: PR-2 Denial Code

6. PR-3 – Copayment Amount

PR-3 indicates the patient is responsible for a required copayment under their health insurance policy.

Learn more: PR-3 Denial Code

7. PR-96 – Non-Covered Charges

PR-96 means the insurance plan does not cover the billed service.

Providers should review the patient's benefits before billing the patient.

Learn more: PR-96 Denial Code

8. OA-23 – Prior Payer Information

OA-23 generally indicates the claim has been adjusted based on another payer's payment or coordination of benefits information.

Providers should review previous payer adjudication before resubmitting claims.

Learn more: OA-23 Denial Code

9. OA-94 – Special Payment Policy

OA-94 indicates the claim was processed under a special Medicare or payer-specific payment policy.

Providers should review the remittance advice for additional details.

Learn more: OA-94 Denial Code

10. CO-123 – Authorization or Benefit Issues

CO-123 generally indicates payment was affected because authorization requirements or plan benefits were not met.

Providers should review the payer's explanation before determining whether a corrected claim or appeal is appropriate.

Learn more: CO-123 Denial Code

How To Reduce Common Denial Codes

Many of these denials can be prevented by:

  • Verifying insurance eligibility before every visit.

  • Reviewing patient demographics.

  • Confirming prior authorization requirements.

  • Checking claims for missing information.

  • Reviewing coding accuracy before submission.

Small improvements in claim accuracy can significantly reduce denial rates over time.

Frequently Asked Questions

Which denial code is most common?

CO-16 is one of the most frequently encountered denial codes because missing or incomplete claim information is a common billing issue.

Should every denial be appealed?

No. Some denials require corrected claims rather than formal appeals.

Can providers prevent most denial codes?

Many denial codes can be reduced through proper insurance verification, accurate coding, complete documentation, and careful claim review before submission.

Where can I learn more about a specific denial code?

Each denial code has its own dedicated guide explaining its meaning, common causes, and recommended next steps.

Related Articles
  • What Is A Claim Adjustment Reason Code (CARC)?

  • How To Read Medical Billing Denial Codes

  • Understanding CARC and RARC Codes

  • How To Reduce Medical Billing Claim Denials

Quick Summary

Although hundreds of medical billing denial codes exist, a small group appears most frequently during claim processing. Understanding common denial codes such as CO-16, CO-18, CO-22, PR-1, PR-2, PR-3, PR-96, OA-23, OA-94, and CO-123 helps healthcare providers resolve claims more efficiently and improve reimbursement outcomes.

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